Stoichiometry of HLA Class II-Invariant Chain Oligomers
نویسندگان
چکیده
منابع مشابه
Stoichiometry of HLA Class II-Invariant Chain Oligomers
BACKGROUND The HLA gene complex encodes three class II isotypes, DR, DQ, and DP. HLA class II molecules are peptide receptors that present antigens for recognition by T lymphocytes. In antigen presenting cells, the assembly of matched α and β subunits to heterodimers is chaperoned by invariant chain (Ii). Ii forms a homotrimer with three binding sites for class II heterodimers. The current mode...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0017257